Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752727 | 0.72 | GAA (0.47) | NAAA | |
| SCHEMBL9800835 | 0.71 | FAAH (0.35) | NAAA | |
| SCHEMBL5656501 | 0.69 | DPP4 (0.33) | — | |
| SCHEMBL10754940 | 0.69 | EPHX1 (0.46) | NAAA | |
| SCHEMBL10755785 | 0.69 | RAB9A (0.46) | — | |
| SCHEMBL10649367 | 0.69 | KDM4E (0.36) | — | |
| SCHEMBL8894148 | 0.68 | POLB (0.45) | — | |
| SCHEMBL10758102 | 0.67 | PSMB5 (0.36) | NAAA | |
| SCHEMBL10867385 | 0.67 | CYP2C19 (0.31) | — | |
| SCHEMBL10757168 | 0.66 | PTGS1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675399-A | N-HYDROXY-2-AZETIDINONES; ACYLATION, SOLVOLYSIS | NOTRE DAME UNIVERSITY (US) | 1987-06-23 | — | — | US | disclosed |
| US-4565654-A | BETA-LACTAMASE ENZYME INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0123442-A1 | Improvements in or relating to a process for producing beta-lactam compounds | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-10-31 | — | — | EP | disclosed |