Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.64 |
| ▸ | CTSK | P43235 | 1/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.50 |
| ▸ | GNPAT | O15228 | 1/20 | 0.50 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.50 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.50 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.50 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.50 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.50 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.50 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.50 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22927776 | 0.86 | CTSS (0.67) | CTSSCTSKCTSLCTSBGNPAT | |
| SCHEMBL14476767 | 0.85 | CTSS (0.65) | CTSSCTSKCTSLCTSBGNPAT | |
| SCHEMBL10695717 | 0.83 | CTSS (0.62) | CTSSCTSKGNPATOPRD1OPRM1 | |
| SCHEMBL29434528 | 0.81 | CTSS (0.60) | CTSSCTSKGNPATPAMOPRD1 | |
| SCHEMBL14113860 | 0.80 | CTSS (0.74) | CTSSCTSKCTSLCTSBGNPAT | |
| SCHEMBL23376600 | 0.80 | CTSS (0.68) | CTSSCTSKGNPATPAMTACR1 | |
| SCHEMBL13956933 | 0.80 | CTSS (0.68) | CTSSCTSKGNPATPAMTACR1 | |
| SCHEMBL8441334 | 0.80 | CTSS (0.68) | CTSSCTSKCTSLCTSBGNPAT | |
| SCHEMBL10800036 | 0.79 | CTSS (0.76) | CTSSCTSKCTSLCTSBGNPAT | |
| SCHEMBL10800041 | 0.79 | CTSS (0.76) | CTSSCTSKCTSLCTSBGNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642205-A | Diastereomer salts of phenylalanine and N-acyl derivatives thereof and process for the separation of optically active phenylalanine and N-acyl derivatives thereof | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-02-10 | — | — | US | claimed |
| EP-0174358-A1 | NOVEL DIASTEREOMER SALTS OF PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF AND PROCESS FOR THE SEPARATION OF OPTICALLY ACTIVE PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF | ALKALOIDA VEGYéSZETI GYáR (HU) | 1986-03-19 | — | — | EP | claimed |
| WO-1985003932-A1 | NOVEL DIASTEREOMER SALTS OF PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF AND PROCESS FOR THE SEPARATION OF OPTICALLY ACTIVE PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1985-09-12 | — | — | WO | claimed |
| US-4642205-A | Diastereomer salts of phenylalanine and N-acyl derivatives thereof and process for the separation of optically active phenylalanine and N-acyl derivatives thereof | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-02-10 | — | — | US | disclosed |
| EP-0174358-A1 | NOVEL DIASTEREOMER SALTS OF PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF AND PROCESS FOR THE SEPARATION OF OPTICALLY ACTIVE PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF | ALKALOIDA VEGYéSZETI GYáR (HU) | 1986-03-19 | — | — | EP | disclosed |
| WO-1985003932-A1 | NOVEL DIASTEREOMER SALTS OF PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF AND PROCESS FOR THE SEPARATION OF OPTICALLY ACTIVE PHENYLALANINE AND N-ACYL DERIVATIVES THEREOF | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1985-09-12 | — | — | WO | disclosed |