SCHEMBL10695717

SCHEMBL10695717

CC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 1/20 0.62
▸ CTSK P43235 1/20 0.62
▸ OPRD1 P41143 5/20 0.56
▸ OPRM1 P35372 4/20 0.56
▸ OPRK1 P41145 1/20 0.56
▸ GNPAT O15228 1/20 0.52
▸ REN P00797 1/20 0.52
▸ LTA4H P09960 2/20 0.50
▸ MME P08473 1/20 0.50
▸ ANPEP P15144 1/20 0.50
▸ ECE1 P42892 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29434521 0.90 OPRD1 (0.60) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL29434528 0.88 CTSS (0.60) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL29613059 0.88 REN (0.55) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL31388294 0.88 OPRD1 (0.57) CTSSOPRD1OPRM1OPRK1REN
SCHEMBL28549280 0.86 REN (0.59) CTSSOPRD1OPRM1OPRK1REN
SCHEMBL28549277 0.86 REN (0.59) CTSSOPRD1OPRM1OPRK1REN
SCHEMBL11113189 0.86 CTSS (0.63) CTSSCTSKGNPATLTA4HMME
SCHEMBL9571894 0.86 CTSS (0.63) CTSSCTSKGNPATLTA4HMME
SCHEMBL9571896 0.86 CTSS (0.63) CTSSCTSKGNPATLTA4HMME
SCHEMBL22927776 0.85 CTSS (0.67) CTSSCTSKOPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590273-B2 Stabilized glycoside hydrolase variants NOVOZYMES A/S (DK) 2026-03-31 — — US disclosed
US-12391934-B2 Stabilized cellulase variants NOVOZYMES A/S (DK) 2025-08-19 — — US disclosed
EP-3953463-B1 STABILIZED GLYCOSIDE HYDROLASE VARIANTS NOVOZYMES AS (DK) 2025-08-06 — — EP disclosed
US-20250084394-A1 STABILIZED CELLULASE VARIANTS NOVOZYMES A/S (DK) 2025-03-13 — — US disclosed
US-12129498-B2 Stabilized endoglucanase variants NOVOZYMES A/S (DK) 2024-10-29 — — US disclosed
CN-118530973-A Stabilized cellulase variants 诺维信公司 2024-08-23 — — CN disclosed
CN-118460512-A Stabilized cellulase variants 诺维信公司 2024-08-09 — — CN disclosed
CN-112204137-B Stabilized cellulase variants 诺维信公司 2024-05-14 — — CN disclosed
CN-112272701-B Stabilized cellulase variants 诺维信公司 2024-05-14 — — CN disclosed
US-20230295591-A1 STABILIZED CELLULASE VARIANTS NOVOZYMES A/S (DK) 2023-09-21 — — US disclosed
US-20230143128-A1 CARBOHYDRATE BINDING MODULE VARIANTS NOVOZYMES A/S (DK) 2023-05-11 — — US disclosed
EP-4133066-A1 CARBOHYDRATE BINDING MODULE VARIANTS Novozymes A/S (DK) 2023-02-15 — — EP disclosed
US-11566239-B2 Stabilized cellulase variants NOVOZYMES A/S (DK) 2023-01-31 — — US disclosed
CN-115210371-A Carbohydrate binding module variants 诺维信公司 2022-10-18 — — CN disclosed
US-20220186151-A1 STABILIZED GLYCOSIDE HYDROLASE VARIANTS NOVOZYMES A/S (DK) 2022-06-16 — — US disclosed
EP-3953463-A1 STABILIZED GLYCOSIDE HYDROLASE VARIANTS Novozymes A/S (DK) 2022-02-16 — — EP disclosed
EP-0263903-A1 Method for preparing specific inhibitors of virus-specified proteases E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-04-20 — — EP disclosed
EP-0263202-A1 Inhibition of viral protease activity by peptide halomethyl ketones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-04-13 — — EP disclosed
US-4644055-A HALOMETHYL KETONE OR METHYL KETONE COVALENTLY LINKED TO PEPTIDE SEQUENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-02-17 — — US disclosed
US-4636492-A ENZYME INHIBITORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143128-A1 CARBOHYDRATE BINDING MODULE VARIANTS MGAM, MANBA, MAN2B1 CTSS 811/4885CTSK 1234/4885OPRD1 4592/4885
US-12590273-B2 Stabilized glycoside hydrolase variants IDUA, IDE, TREH CTSS 900/4885CTSK 1797/4885OPRD1 4560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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