SCHEMBL10759607

SCHEMBL10759607

C/C(C(N)=O)=C(\N)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10759619 1.00 LMNA (0.39) LMNAALOX15BLMPMP22TDP1
SCHEMBL2959058 0.80 LMNA (0.37) LMNAALOX15BLMPMP22TDP1
SCHEMBL2959060 0.80 LMNA (0.37) LMNAALOX15BLMPMP22TDP1
SCHEMBL2713252 0.77 LMNA (0.39) LMNAALOX15BLMPMP22TDP1
SCHEMBL15710985 0.77 LMNA (0.39) LMNAALOX15BLMPMP22TDP1
SCHEMBL15710980 0.77 LMNA (0.39) LMNAALOX15BLMPMP22TDP1
SCHEMBL9848850 0.75
SCHEMBL10762991 0.74 LMNA (0.32) LMNAALOX15BLMPMP22
SCHEMBL4779556 0.73 LMNA (0.58) LMNAALOX15BLMPMP22TDP1
SCHEMBL4141273 0.73 LMNA (0.58) LMNAALOX15BLMPMP22TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4647606-A Blend of rapid set asphaltic emulsion with slow set asphalt emulsion OWENS-CORNING FIBERGLAS CORPORATION (US) 1987-03-03 US disclosed
US-4547225-A Additives for hot mix asphalt OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-10-15 US disclosed
EP-0082056-B1 CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-05-22 EP disclosed
US-4456633-A Chip seal technique employing blends of asphaltic emulsions OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-06-26 US disclosed
US-4436864-A Aqueous emulsions of acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-03-13 US disclosed
US-4436767-A Slurry seal method using acrylamide and rubber modified asphaltic emulsion OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-03-13 US disclosed
US-4419489-A Easily emulsifiable acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-12-06 US disclosed
US-4394481-A Cationic arcylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-07-19 US disclosed
WO-1983002115-A1 CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS OWENS CORNING FIBERGLASS CORP (US) 1983-06-23 WO disclosed
EP-0082056-A1 Cationic acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-06-22 EP disclosed
US-4383081-A Cationic acrylamide chemically modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-05-10 US disclosed