SCHEMBL4141273

SCHEMBL4141273

CC(C(N)=O)=C(C)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.58
BLM P54132 2/20 0.58
ALOX15 P16050 1/20 0.58
PMP22 Q01453 1/20 0.58
TDP1 Q9NUW8 3/20 0.53
LDHA P00338 2/20 0.43
LDHB P07195 1/20 0.43
ALDH1A1 P00352 5/20 0.42
OR51E2 Q9H255 1/20 0.42
CRBN Q96SW2 1/20 0.39
TSHR P16473 2/20 0.39
ACHE P22303 1/20 0.39
THPO P40225 1/20 0.39
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CA1 P00915 2/20 0.36
TAS2R38 P59533 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27696587 1.00 LMNA (0.58) LMNABLMALOX15PMP22TDP1
SCHEMBL4779556 1.00 LMNA (0.58) LMNABLMALOX15PMP22TDP1
SCHEMBL27476647 0.96 LMNA (0.54) LMNABLMALOX15PMP22TDP1
SCHEMBL2631747 0.89 LMNA (0.47) LMNABLMALOX15PMP22TDP1
SCHEMBL343159 0.86 LDHA (0.50) LMNABLMALOX15PMP22TDP1
SCHEMBL343160 0.86 LDHA (0.50) LMNABLMALOX15PMP22TDP1
SCHEMBL2999475 0.86 LDHA (0.50) LMNABLMALOX15PMP22TDP1
SCHEMBL3360476 0.84
SCHEMBL11464126 0.84
SCHEMBL10474718 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140194589-A1 WATER-DISPERSIBLE AMPHOTERIC POLYURETHANE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN REINFORCING CONCRETE JIANGSU RESEARCH INSTITUTE OF BUILDING SCIENCE CO. LTD (CN) 2014-07-10 US claimed
EP-2730595-A1 WATER-DISPERSIBLE AMPHOTERIC POLYURETHANE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN REINFORCING CONCRETE Jiangsu Sobute New Materials Co., Ltd. (CN) 2014-05-14 EP claimed
EP-0653202-A1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent L'OREAL (FR) 1995-05-17 EP claimed
CN-116421719-A PEG (polyethylene glycol) shedding and double-sensitivity nano-drug and preparation method and application thereof 广州医科大学附属第二医院 2023-07-14 CN disclosed
CN-114081948-A PH-responsive nanoparticle self-assembled aggregate molecular probe and preparation method and application thereof 无锡市人民医院 2022-02-25 CN disclosed
US-20140194589-A1 WATER-DISPERSIBLE AMPHOTERIC POLYURETHANE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN REINFORCING CONCRETE JIANGSU RESEARCH INSTITUTE OF BUILDING SCIENCE CO. LTD (CN) 2014-07-10 US disclosed
EP-2730595-A1 WATER-DISPERSIBLE AMPHOTERIC POLYURETHANE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN REINFORCING CONCRETE Jiangsu Sobute New Materials Co., Ltd. (CN) 2014-05-14 EP disclosed
US-20090131657-A1 PROCESS FOR ALKENYLATING CARBOXAMIDES BASF SE (DE) 2009-05-21 US disclosed
WO-2008138621-A2 SYNTHESIS OF AMINOCYCLOPENTANE CARBOXYLIC ACIDS FAUST PHARMACEUTICALS (FR) 2008-11-20 WO disclosed
EP-1992610-A1 New route of synthesis Faust Pharmaceuticals (FR) 2008-11-19 EP disclosed
CN-1260263-C Preparation of amphoteric polyurethane resin and products thereby and amphoteric resin composition NAT STARCH CHEM INVEST (US) 2006-06-21 CN disclosed
CN-1406996-A Preparation of amphoteric polyurethane resin and products thereby and amphoteric resin composition NAT STARCH CHEM INVEST (US) 2003-04-02 CN disclosed
CN-1332205-A Radiation-sensitive resin composition JSR CORP (JP) 2002-01-23 CN disclosed
EP-0953020-A1 RADIATION CURABLE CONDUCTIVE COATING DISPERSION, PROCESS FOR ITS PREPARATION AND COATINGS MADE OF IT DSM N.V. (NL) 1999-11-03 EP disclosed
WO-1998031754-A1 RADIATION CURABLE CONDUCTIVE COATING DISPERSION, PROCESS FOR ITS PREPARATION AND COATINGS MADE OF IT DSM N.V. (NL) 1998-07-23 WO disclosed
US-5700454-A FOR PERMANENT WAVING OF HAIR WITH IMPROVED CURLING EFFICIENCY L'OREAL (FR) 1997-12-23 US disclosed
EP-0653202-A1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent L'OREAL (FR) 1995-05-17 EP disclosed
CN-1008101-B PROCESS OF PRODUCTION FOR POLYPHENYL ETHER ASAHI CHEMICAL IND (JP) 1990-05-23 CN disclosed
CN-87107289-A The production method of polyphenylene oxide 1988-06-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131657-A1 PROCESS FOR ALKENYLATING CARBOXAMIDES PRMT5, CYC1, CBR3 LMNA 2037/4885BLM 3120/4885ALOX15 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.