Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCND3 | P30281 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.40 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580149 | 0.86 | CDK4 (0.41) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10747834 | 0.85 | PDE2A (0.41) | NPBWR1SCN9ANR1I2PDE5APDE3B | |
| SCHEMBL10746096 | 0.84 | CYP17A1 (0.46) | NR1I2PTGS2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10577379 | 0.84 | CDK4 (0.40) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10765238 | 0.83 | CDK4 (0.45) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10577387 | 0.83 | CDK4 (0.39) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10748145 | 0.82 | DGAT1 (0.48) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10579306 | 0.81 | CDK4 (0.38) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL10762025 | 0.81 | CDK4 (0.59) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL11021893 | 0.80 | ATR (0.44) | CDK4CCNA2CCND1CDK2CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209707-A2 | 2-Aryl imidazoles, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |