Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761091 | 1.00 | PTGS2 (0.58) | PTGS2PTGS1LMNANPC1RAB9A | |
| SCHEMBL10762714 | 0.83 | LMNA (0.59) | PTGS2PTGS1LMNANPC1RAB9A | |
| SCHEMBL10762705 | 0.83 | LMNA (0.59) | PTGS2PTGS1LMNANPC1RAB9A | |
| SCHEMBL10762889 | 0.81 | PTGS1 (0.72) | PTGS2PTGS1LMNANPC1RAB9A | |
| SCHEMBL10760245 | 0.81 | PTGS2 (0.61) | PTGS2PTGS1LMNANPC1RAB9A | |
| SCHEMBL10762887 | 0.81 | PTGS1 (0.72) | PTGS2PTGS1LMNANPC1RAB9A | |
| SCHEMBL10760249 | 0.81 | PTGS2 (0.61) | PTGS2PTGS1LMNANPC1RAB9A | |
| SCHEMBL10763636 | 0.80 | NQO2 (0.38) | PTGS2PTGS1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL10763632 | 0.80 | NQO2 (0.38) | PTGS2PTGS1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL10760692 | 0.80 | PTGS2 (0.57) | PTGS2PTGS1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |