Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 3/20 | 0.60 |
| ▸ | CTSC | P53634 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10765164 | 0.98 | EED (0.63) | EEDCTSCLMNATDP1MME | |
| SCHEMBL10760562 | 0.88 | EED (0.52) | EEDCTSCACEALDH1A1POLB | |
| SCHEMBL3919067 | 0.83 | ITGB3 (0.51) | EEDACE | |
| SCHEMBL29576554 | 0.78 | EED (0.47) | EEDCTSCLMNAPRMT5WDR77 | |
| SCHEMBL30712861 | 0.77 | EED (0.54) | EEDCTSCMMEACEACE2 | |
| SCHEMBL31026629 | 0.77 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL28122660 | 0.77 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL601567 | 0.77 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL21808154 | 0.77 | CTSC (0.68) | CTSCLMNATDP1MMEACE | |
| SCHEMBL28122659 | 0.77 | CTSC (0.68) | CTSCLMNATDP1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214570-A2 | N-alkylated tripeptides, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-18 | — | — | EP | disclosed |