Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 3/20 | 0.52 |
| ▸ | CTSC | P53634 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761203 | 0.88 | EED (0.60) | EEDCTSCALDH1A1ACEPOLB | |
| SCHEMBL10765164 | 0.86 | EED (0.63) | EEDCTSCALDH1A1ACE | |
| SCHEMBL3919067 | 0.83 | ITGB3 (0.51) | EEDTACR1ACE | |
| SCHEMBL26624221 | 0.81 | TSHR (0.46) | EEDCTSCTSHRCYP3A4ALDH1A1 | |
| SCHEMBL10593398 | 0.80 | TSHR (0.60) | TSHRALDH1A1 | |
| SCHEMBL4052801 | 0.80 | TSHR (0.60) | TSHRALDH1A1 | |
| SCHEMBL8060653 | 0.80 | TSHR (0.60) | TSHRALDH1A1 | |
| SCHEMBL14374266 | 0.80 | TSHR (0.60) | TSHRALDH1A1 | |
| SCHEMBL10593392 | 0.80 | TSHR (0.60) | TSHRALDH1A1 | |
| SCHEMBL9734685 | 0.80 | TSHR (0.60) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214570-A2 | N-alkylated tripeptides, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-18 | — | — | EP | disclosed |