Benzene

Benzene

SCHEMBL107628

O=S(=O)(Cl)Cl.c1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTR6 P50406 1/20 0.35
TSHR P16473 2/20 0.33
TP53 P04637 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
PLA2G7 Q13093 1/20 0.32
CA9 Q16790 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28311116 1.00 ALDH1A1 (0.47) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL11355839 1.00 ALDH1A1 (0.47) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28136999 0.95 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28004051 0.95 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL27876863 0.95 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28381465 0.95 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL5815569 0.95 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28132429 0.95 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28850209 0.95 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL27440016 0.95 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9646 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157728-A Preparation method of 17 alpha-hydroxy pregna-4-ene-3, 11, 20-trione and intermediate compound prepared by same 湖北共同甾体药物研究院有限公司 2025-06-17 CN claimed
WO-2025094214-A1 Process for the preparation of 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl) benzenesulfonamide and its intermediates thereof MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2025-05-08 WO claimed
CN-119930485-A Preparation method of 2-chloro-3-methyl-4-methylsulfonyl benzoic acid 科莱博(江苏)科技股份有限公司 2025-05-06 CN claimed
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
WO-2024234564-A1 METHOD FOR SYNTHESIZING PLANT ROOT INHIBITOR 湖南维摩科技有限公司 2024-11-21 WO claimed
US-12071418-B2 Processes for preparation of dapagliflozin or its solvates or co-crystals thereof LAURUS LABS LIMITED (IN) 2024-08-27 US claimed
US-20240228451-A1 METHODS OF SYNTHESIZING LIPSTATIN DERIVATIVES PANAFINA, INC. 2024-07-11 US claimed
CN-115850199-B Preparation method of high-purity sodium sulfaisoxazole 天和药业有限公司 2024-05-03 CN claimed
CN-108863857-B Continuous dilution device and method for cooling crystallization of acetamido benzenesulfonyl chloride 浙江龙盛化工研究有限公司 2024-04-30 CN claimed
CN-117903020-A Preparation method of diphenyl sulfone 南通沃兰化工有限公司 2024-04-19 CN claimed
US-4710562-A Stabilizing polyaryletherketones AMOCO CORPORATION (US) 1987-12-01 US claimed
EP-0226099-A2 N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1987-06-24 EP claimed
CN-85109326-A Stainless steel-silicon carbide acidity electrode and autofrettage 1987-02-11 CN claimed
US-4377703-A Process for preparing benzoxanthene and benzothioxanthene dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-03-22 US claimed
EP-0050020-A2 Cold set phenolic resins BP Chemicals Limited (GB) 1982-04-21 EP claimed
US-4289814-A Stabilized phenolic resins THE DOW CHEMICAL CO. 1981-09-15 US claimed
US-4252738-A 1,2-Halohydrincarboxylic acid esters and a process for their preparation BAYER AKTIENGESELLSCHAFT (DE) 1981-02-24 US claimed
US-4012442-A FRIEDEL-CRAFTS CATALYST, BENZENE SULFONYL CHLORIDE, CHLORINE BAYER AKTIENGESELLSCHAFT (DT) 1977-03-15 US claimed
US-3952065-A ACTIVATED CARBON-PHOSPHORUS HALIDE OR AZO CATALYST, DECOMPOSITION VYSKUMNY USTAV AGROCHEMICKEJ TECHNOLOGIE (CS) 1976-04-20 US claimed
US-3946072-A ARENE-METAL TRICARBONYL COMPLEXES AS CATALYSTS, ALKYLATION, ACYLATION THE UNIVERSITY OF AKRON (US) 1976-03-23 US claimed