Benzene

Benzene

SCHEMBL5815569

C.O=S(=O)(Cl)Cl.O=S(=O)(Cl)Cl.c1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTR6 P50406 1/20 0.33
TSHR P16473 2/20 0.30
TP53 P04637 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
PLA2G7 Q13093 1/20 0.30
CA9 Q16790 1/20 0.30
CA13 Q8N1Q1 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28381465 1.00 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28311116 0.95 ALDH1A1 (0.47) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL107628 0.95 ALDH1A1 (0.47) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL11355839 0.95 ALDH1A1 (0.47) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28850209 0.90 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28295157 0.90 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL27440016 0.90 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28136999 0.90 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28004051 0.90 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR
Benzene SCHEMBL28147740 0.90 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HTR6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006095359-A1 SYNTHESIS OF 2-DEOXY-2, 2-DI FLUORO-D-RIBO FURANOSE-3, 5 DI(4-METHY/4-NITRO-CHLORO)BENZOATE AND ITS CONVERSION TO GEMCITABINE HYDROCHLORIDE THEREOF SMS PHARMACEUTICALS LIMITED (IN) 2006-09-14 WO claimed