Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761349 | 0.86 | RAB9A (0.53) | PTGS1PTGS2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10763307 | 0.83 | PTGS1 (0.58) | PTGS1PTGS2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10762077 | 0.81 | PTGS1 (0.68) | PTGS1PTGS2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10765577 | 0.79 | PDE3B (0.47) | PTGS1PTGS2PDE3BPDE3AMAOB | |
| SCHEMBL10761925 | 0.78 | PTGS2 (0.53) | PTGS1PTGS2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10760345 | 0.78 | RAB9A (0.53) | PTGS1PTGS2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10763395 | 0.78 | SMN1; SMN2 (0.53) | PTGS1PTGS2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10766165 | 0.76 | PTGS2 (0.58) | PTGS1PTGS2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10762761 | 0.76 | PTGS1 (0.58) | PTGS1PTGS2LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10759912 | 0.76 | PTGS1 (0.57) | PTGS1PTGS2LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |