Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22275552 | 0.87 | RAB9A (0.60) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11016974 | 0.84 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11017647 | 0.84 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11016594 | 0.84 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11018932 | 0.84 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11015017 | 0.84 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11016694 | 0.83 | RAB9A (0.58) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL25987595 | 0.82 | MAPT (0.58) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL16769385 | 0.82 | MAPT (0.58) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11018925 | 0.82 | RAB9A (0.57) | ALDH1A1RAB9ASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711888-A | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0210044-A2 | Hydroxy and alkoxy pyrimidines | PFIZER INC. (US) | 1987-01-28 | — | — | EP | disclosed |