Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763589 | 0.84 | RAB9A (0.63) | PTGS1PTGS2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10760906 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10759912 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10765022 | 0.81 | PTGS2 (0.54) | PTGS1PTGS2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10766806 | 0.80 | RAB9A (0.60) | PTGS1PTGS2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10762033 | 0.78 | PTGS1 (0.71) | PTGS1PTGS2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10762053 | 0.78 | PTGS1 (0.71) | PTGS1PTGS2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10763427 | 0.78 | PTGS1 (0.71) | PTGS1PTGS2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10762040 | 0.78 | PTGS1 (0.71) | PTGS1PTGS2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL10763316 | 0.77 | PDE3B (0.50) | PTGS1PTGS2GAAPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |