Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.68 |
| ▸ | DRD2 | P14416 | 3/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10765127 | 1.00 | SIGMAR1 (0.68) | SIGMAR1DRD2DRD3SLC6A12 | |
| SCHEMBL10355539 | 0.89 | DRD2 (0.80) | DRD2DRD3 | |
| SCHEMBL10762595 | 0.87 | DRD3 (0.77) | SIGMAR1DRD2DRD3 | |
| SCHEMBL8526550 | 0.84 | SIGMAR1 (0.74) | SIGMAR1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9091535 | 0.83 | SIGMAR1 (0.73) | SIGMAR1DRD2DRD3 | |
| SCHEMBL8528423 | 0.82 | SIGMAR1 (0.81) | SIGMAR1DRD2DRD3 | |
| SCHEMBL10695864 | 0.82 | SIGMAR1 (0.77) | SIGMAR1DRD2DRD3 | |
| SCHEMBL9549999 | 0.81 | SIGMAR1 (0.69) | SIGMAR1DRD2DRD3 | |
| SCHEMBL9550009 | 0.81 | SIGMAR1 (0.69) | SIGMAR1DRD2DRD3 | |
| SCHEMBL11072498 | 0.81 | DRD2 (0.79) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207913-A1 | Catechol carboxamides, process for their preparation, intermediates and a pharmaceutical preparation | Astra Läkemedel Aktiebolag (SE) | 1987-01-07 | — | — | EP | disclosed |
| WO-1986007591-A1 | CATECHOLCARBOXAMIDES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND A PHARMACEUTICAL PREPARATION | Astra Läkemedel Aktiebolag (SE) | 1986-12-31 | — | — | WO | disclosed |