Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762143 | 0.91 | PTGS2 (0.63) | PTGS2PTGS1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10766220 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10760269 | 0.81 | PTGS2 (0.65) | PTGS2PTGS1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10759679 | 0.80 | SMN1; SMN2 (0.59) | PTGS2PTGS1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10760909 | 0.80 | PTGS2 (0.70) | PTGS2PTGS1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10766295 | 0.79 | PDE3A (0.46) | PTGS2PTGS1PDE4BPDE3BPDE3A | |
| SCHEMBL10760786 | 0.79 | PTGS2 (0.66) | PTGS2PTGS1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10762879 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10764503 | 0.78 | SMN1; SMN2 (0.60) | PTGS2PTGS1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10763589 | 0.78 | RAB9A (0.63) | PTGS2PTGS1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |