Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 14/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764735 | 0.92 | PDE3A (0.45) | PDE3APDE3BPDE4BPDE4APDE4C | |
| SCHEMBL10763474 | 0.86 | PDE3A (0.50) | PDE3APDE3BPDE4BPDE4APDE4C | |
| SCHEMBL10761165 | 0.86 | PDE3A (0.47) | PDE3APDE3BPDE4BPDE4APDE4C | |
| SCHEMBL10771165 | 0.82 | PDE3A (0.40) | PDE3APDE3BPDE4BPDE4APDE4C | |
| SCHEMBL10764072 | 0.81 | PDE3B (0.57) | PDE3APDE3BPDE4BPDE4APDE4C | |
| SCHEMBL10762648 | 0.81 | RAB9A (0.54) | PDE3APDE3BPDE4BPDE4APDE4C | |
| SCHEMBL10766102 | 0.81 | PDE3B (0.58) | PDE3APDE3BPDE4BPDE4APDE4C | |
| SCHEMBL10766791 | 0.80 | PDE3B (0.46) | PDE3APDE3BPDE4BPDE4APDE4C | |
| SCHEMBL10766381 | 0.80 | PDE3A (0.50) | PDE3APDE3BPDE4BPDE4APDE4C | |
| SCHEMBL10761200 | 0.80 | PDE3A (0.46) | PDE3APDE3BPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |