Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 12/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 12/20 | 0.57 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766791 | 0.87 | PDE3B (0.46) | PDE3BPDE3APNMTPBRM1PDE4A | |
| SCHEMBL10759798 | 0.83 | PDE3B (0.59) | PDE3BPDE3ASMN1; SMN2LMNAMAPT | |
| SCHEMBL10760276 | 0.83 | PDE3B (0.61) | PDE3BPDE3ASMN1; SMN2LMNARAB9A | |
| SCHEMBL10765683 | 0.81 | PDE3A (0.45) | PDE3BPDE3ASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL10764735 | 0.81 | PDE3A (0.45) | PDE3BPDE3ASMN1; SMN2LMNAMAPT | |
| SCHEMBL10760260 | 0.81 | PDE3B (0.42) | PDE3BPDE3APNMTPBRM1 | |
| SCHEMBL10765623 | 0.80 | PDE3A (0.43) | PDE3BPDE3ALMNAMAPTPBRM1 | |
| SCHEMBL10764416 | 0.79 | PDE3A (0.40) | PDE3BPDE3APNMTPBRM1PDE4B | |
| SCHEMBL10761085 | 0.79 | PDE3B (0.54) | PDE3BPDE3ASMN1; SMN2LMNAMAPT | |
| SCHEMBL10760541 | 0.78 | PDE3B (0.56) | PDE3BPDE3ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |