Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762053 | 0.82 | PTGS1 (0.71) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10760169 | 0.82 | PTGS1 (0.59) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10766165 | 0.81 | PTGS2 (0.58) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10765902 | 0.80 | SMN1; SMN2 (0.69) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10762040 | 0.80 | PTGS1 (0.71) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10763427 | 0.80 | PTGS1 (0.71) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10762033 | 0.80 | PTGS1 (0.71) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10762432 | 0.79 | PTGS1 (0.70) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10762011 | 0.79 | RAB9A (0.63) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10764269 | 0.79 | RAB9A (0.63) | LMNARAB9ASMN1; SMN2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210530-A1 | 6-Arylalkenyl pyridazinones | MERCK PATENT GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |