Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198842 | 0.86 | CES2 (0.73) | CES2CES1PTGS2MAPTHTT | |
| SCHEMBL28735064 | 0.86 | CES2 (0.73) | CES2CES1PTGS2MAPTHTT | |
| SCHEMBL10764097 | 0.84 | MEN1 (0.62) | CES2CES1MAPK13MAPK12MAPK11 | |
| SCHEMBL6203654 | 0.82 | CES2 (0.68) | CES2CES1PTGS2MAPTMAPK1 | |
| SCHEMBL11554973 | 0.79 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL10765485 | 0.77 | CES2 (0.55) | CES2CES1MAPTNPC1RAB9A | |
| SCHEMBL10476789 | 0.76 | CES2 (0.67) | CES2CES1MAPTRAB9AHTT | |
| SCHEMBL9479942 | 0.76 | ALDH1A1 (0.72) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL1118626 | 0.76 | ALDH1A1 (0.72) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL27873258 | 0.76 | MAPK13 (0.58) | MAPK13MAPK12MAPK11MAPK14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207728-A2 | Novel pyrazoline compounds, process for production thereof, and insecticides containing them as active ingredients | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1987-01-07 | — | — | EP | disclosed |