Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8110954 | 0.83 | GAA (0.75) | GAAKMT2ALMNAMEN1CYP2C19 | |
| SCHEMBL9297476 | 0.83 | KMT2A (0.75) | GAAKMT2ALMNAMEN1MAPT | |
| SCHEMBL7088595 | 0.81 | ALDH1A1 (0.57) | GAAKMT2ALMNAMEN1MAPT | |
| SCHEMBL30163598 | 0.81 | ALDH1A1 (0.57) | GAAKMT2ALMNAMEN1MAPT | |
| SCHEMBL1791238 | 0.81 | GAA (0.73) | GAAKMT2ALMNAMEN1CYP2C19 | |
| SCHEMBL9312776 | 0.81 | GAA (0.84) | GAAKMT2ALMNAMEN1CYP2C19 | |
| SCHEMBL31527868 | 0.81 | GAA (0.73) | GAAKMT2ALMNAMEN1CYP2C19 | |
| SCHEMBL1645837 | 0.81 | GAA (0.73) | GAAKMT2ALMNAMEN1MAPT | |
| SCHEMBL2835288 | 0.81 | GAA (0.73) | GAAKMT2ALMNAMEN1CYP2C19 | |
| SCHEMBL23169602 | 0.81 | GAA (0.55) | GAAKMT2ALMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239170-A1 | Stabilized lactam polymerization solutions | DSM RIM NYLON V.O.F (NL) | 1987-09-30 | — | — | EP | disclosed |
| US-4694039-A | Stabilized lactam polymerization solutions | DSM RIM NYLON V.O.F. (NL) | 1987-09-15 | — | — | US | disclosed |
| US-4672085-A | LACTAM SUBSTITUTED POLYBUTADIENE INITIATOR,TRISUBTITED UREA STABILIZER;NYLON BLOCK COPOLYMERS | DSM RIM NYLON VOF (NL) | 1987-06-09 | — | — | US | disclosed |