SCHEMBL1645837

SCHEMBL1645837

CCOc1ccccc1NC(C)=O

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.73
MAPT P10636 2/20 0.69
BRD4 O60885 1/20 0.69
KMT2A Q03164 4/20 0.65
CYP2C19 P33261 1/20 0.65
KDM4E B2RXH2 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
ALDH1A1 P00352 4/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
MEN1 O00255 2/20 0.64
HPGD P15428 1/20 0.64
HSD17B10 Q99714 1/20 0.62
LMNA P02545 3/20 0.61
MCL1 Q07820 1/20 0.61
POLB P06746 1/20 0.61
TSHR P16473 2/20 0.60
EGFR P00533 1/20 0.60
NPC1 O15118 1/20 0.60
PTK2 Q05397 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14305179 0.89 HSD17B10 (0.70) GAAMAPTBRD4KMT2AL3MBTL1
SCHEMBL11546122 0.87 LMNA (0.75) GAAMAPTBRD4KMT2AKDM4E
SCHEMBL8110954 0.87 GAA (0.75) GAAKMT2ACYP2C19KDM4EL3MBTL1
SCHEMBL9297476 0.87 KMT2A (0.75) GAAMAPTKMT2ACYP2C19KDM4E
SCHEMBL7959649 0.86 RAB9A (0.67) GAAMAPTBRD4KMT2AKDM4E
SCHEMBL31527868 0.86 GAA (0.73) GAAKMT2ACYP2C19KDM4EL3MBTL1
SCHEMBL9312776 0.86 GAA (0.84) GAAKMT2ACYP2C19KDM4EL3MBTL1
SCHEMBL1791238 0.86 GAA (0.73) GAAKMT2ACYP2C19KDM4EL3MBTL1
SCHEMBL2835288 0.86 GAA (0.73) GAAKMT2ACYP2C19KDM4EL3MBTL1
SCHEMBL7956544 0.85 KMT2A (0.72) GAAMAPTBRD4KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4665239-B2 2011-04-06 JP claimed
EP-1412407-A2 MODIFIED AMINOPLAST CROSSLINKERS AND POWDER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG Industries Ohio, Inc. (US) 2004-04-28 EP claimed
WO-2003011935-A2 MODIFIED AMINOPLAST CROSSLINKERS AND POWDER COATING COMPOSITIONS CONTAINING SUCH CROSSLINKERS PPG INDUSTRIES OHIO, INC. (US) 2003-02-13 WO claimed
JP-2002512230-A 2002-04-23 JP claimed
EP-1071668-A1 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS Du Pont Pharmaceuticals Company (US) 2001-01-31 EP claimed
WO-1999054308-A1 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS DU PONT PHARMACEUTICALS COMPANY (US) 1999-10-28 WO claimed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
WO-2023233994-A1 PHARMACEUTICAL COMPOSITION AND AUTOPHAGY ACTIVATOR 国立大学法人京都大学 2023-12-07 WO disclosed
WO-2022118966-A1 AGENT FOR PROMOTING NUCLEIC ACID MOLECULE UPTAKE INTO CELLS, PHARMACEUTICAL COMPOSITION, AND NOVEL COMPOUND 国立大学法人京都大学 2022-06-09 WO disclosed
CN-113474156-B Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2022-04-29 CN disclosed
CN-113474156-A Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same 东丽株式会社 2021-10-01 CN disclosed
US-10928366-B2 Compositions and methods for combining protein precipitation and solid phase extraction SIGMA-ALDRICH CO. LLC (US) 2021-02-23 US disclosed
EP-1071668-A1 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS Du Pont Pharmaceuticals Company (US) 2001-01-31 EP disclosed
EP-0997463-A1 NAPHTHYRIDINE DERIVATIVES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2000-05-03 EP disclosed
WO-1999054308-A1 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS DU PONT PHARMACEUTICALS COMPANY (US) 1999-10-28 WO disclosed
EP-0486653-B1 METHOD FOR PRESERVING CONTACT LENSES IN ONE STEP DISOP SA (ES) 1996-05-22 EP disclosed
US-4600797-A NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US disclosed
EP-0049711-B1 PROCESS FOR THE PRODUCTION OF NITRO-AMINO-BENZENES BAYER AG (DE) 1984-02-29 EP disclosed
EP-0049711-A1 Process for the production of nitro-amino-benzenes BAYER AG (DE) 1982-04-21 EP disclosed