Glucuronate

Glucuronate

SCHEMBL10769722

O=C(O)[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O.Oc1cccc2cccnc12

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.54
METAP2 P50579 2/20 0.54
METAP1 P53582 2/20 0.54
MMP2 P08253 1/20 0.54
CHRM1 P11229 1/20 0.54
TSHR P16473 1/20 0.54
COMT P21964 1/20 0.54
ADRA1A P35348 1/20 0.54
ALDH1A1 P00352 4/20 0.52
ALOX12 P18054 2/20 0.52
LMNA P02545 2/20 0.52
KDM4E B2RXH2 8/20 0.51
HIF1A Q16665 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
KDM4A O75164 2/20 0.40
EGLN1 Q9GZT9 2/20 0.40
RAB9A P51151 1/20 0.40
HIF1AN Q9NWT6 1/20 0.40
KDM6B O15054 1/20 0.40
KDM6A O15550 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glucuronate SCHEMBL4908209 1.00 HDAC8 (0.54) HDAC8METAP2METAP1MMP2CHRM1
Glucuronate SCHEMBL30642324 0.88 MMP2 (0.51) HDAC8METAP2METAP1MMP2CHRM1
Dextrose SCHEMBL2777597 0.79 MMP2 (0.57) HDAC8METAP2METAP1MMP2CHRM1
B-D-Galactose SCHEMBL360345 0.79 MMP2 (0.57) HDAC8METAP2METAP1MMP2CHRM1
Beta-D-Glucose SCHEMBL360644 0.79 MMP2 (0.57) HDAC8METAP2METAP1MMP2CHRM1
Glucuronate SCHEMBL8935076 0.79 CYP1A2 (0.49) ALDH1A1KDM4ERAB9AERN1KMT2A
Oxyquinoline SCHEMBL28459062 0.77 MMP2 (0.84) HDAC8METAP2METAP1MMP2CHRM1
Pyrene SCHEMBL4521971 0.76 KMT2A (0.41) TSHRALDH1A1KDM4EKMT2AMAPT
Oxyquinoline SCHEMBL28315442 0.75 MMP2 (0.81) HDAC8METAP2METAP1MMP2CHRM1
Oxyquinoline SCHEMBL27477171 0.75 MMP2 (0.81) HDAC8METAP2METAP1MMP2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238243-A1 Method for rapid testing of bacteria for identification Cogent Limited (GB) 1987-09-23 EP claimed