Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127254 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2ATSHRMAPTLMNA | |
| SCHEMBL6746278 | 0.84 | AR (0.54) | SMN1; SMN2KMT2ATSHRMAPTLMNA | |
| SCHEMBL6074194 | 0.82 | PTGS1 (0.57) | SMN1; SMN2KMT2ATSHRMAPTLMNA | |
| SCHEMBL6074318 | 0.82 | PTGS1 (0.57) | SMN1; SMN2KMT2ATSHRMAPTLMNA | |
| SCHEMBL3730012 | 0.81 | MAPT (0.44) | SMN1; SMN2TSHRMAPTLMNAPOLB | |
| SCHEMBL16314627 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2ATSHRMAPTLMNA | |
| SCHEMBL8799683 | 0.81 | CYP1A2 (0.63) | SMN1; SMN2KMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL768290 | 0.81 | KMT2A (0.53) | SMN1; SMN2KMT2ATSHRMAPTALOX15 | |
| SCHEMBL768526 | 0.81 | KMT2A (0.53) | SMN1; SMN2KMT2ATSHRMAPTALOX15 | |
| SCHEMBL6262230 | 0.81 | MAPT (0.57) | SMN1; SMN2KMT2ATSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228192-A2 | Renin-inhibitory oligopeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |