Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10774787 | 0.89 | ALDH1A1 (0.39) | KCNH2HRH3HSD17B10ALDH1A1KDM4E | |
| SCHEMBL10771780 | 0.89 | KCNH2 (0.60) | KCNH2HRH3HSD17B10ALDH1A1KDM4E | |
| SCHEMBL9521886 | 0.87 | KDM4E (0.44) | KCNH2HRH3HSD17B10ALDH1A1KDM4E | |
| SCHEMBL10770586 | 0.84 | ALDH1A1 (0.40) | HSD17B10ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL10769580 | 0.80 | KCNH2 (0.35) | KCNH2HRH3HSD17B10ALDH1A1KDM4E | |
| SCHEMBL10773267 | 0.80 | HSD17B10 (0.39) | HSD17B10ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL9675600 | 0.79 | KDM4E (0.54) | KCNH2HRH3HSD17B10ALDH1A1KDM4E | |
| SCHEMBL10772806 | 0.77 | MAPT (0.38) | HSD17B10ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL10772867 | 0.76 | KCNH2 (0.44) | KCNH2HRH3HSD17B10ALDH1A1KDM4E | |
| SCHEMBL10771546 | 0.76 | KCNH2 (0.36) | KCNH2HRH3PRKD3PIM1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |