Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522474 | 0.88 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10PRKD3 | |
| SCHEMBL10770596 | 0.87 | KCNH2 (0.51) | KDM4EALDH1A1HPGDHSD17B10PRKD3 | |
| SCHEMBL9522606 | 0.86 | LMNA (0.51) | KDM4EALDH1A1HPGDHSD17B10PRKD3 | |
| SCHEMBL9523430 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10PRKD3 | |
| SCHEMBL9675600 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10PRKD3 | |
| SCHEMBL9232558 | 0.84 | LMNA (0.43) | KDM4EALDH1A1HPGDHSD17B10PRKD3 | |
| SCHEMBL9523291 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9523083 | 0.82 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9525823 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10PRKD3 | |
| SCHEMBL10566885 | 0.81 | PRKD3 (0.42) | KDM4EALDH1A1HPGDHSD17B10PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |