Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772790 | 0.90 | NPSR1 (0.39) | CYP4F2CYP4A11POLBNPSR1EGFR | |
| SCHEMBL914783 | 0.87 | TSHR (0.41) | POLBTSHR | |
| SCHEMBL702504 | 0.85 | NPSR1 (0.47) | POLBNPSR1EGFRKCNH2TSHR | |
| SCHEMBL9445932 | 0.83 | NPSR1 (0.41) | POLBNPSR1EGFRKCNH2TSHR | |
| SCHEMBL12212067 | 0.78 | NPSR1 (0.42) | POLBNPSR1EGFRKCNH2TSHR | |
| SCHEMBL2008228 | 0.77 | NPSR1 (0.41) | POLBNPSR1EGFRKCNH2TSHR | |
| SCHEMBL8062014 | 0.75 | GABRA1 (0.44) | CYP4F2CYP4A11NPSR1TSHRMAPT | |
| SCHEMBL916350 | 0.75 | CCNT1 (0.43) | POLBNPSR1EGFRKCNH2TSHR | |
| SCHEMBL916696 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL4538982 | 0.73 | KCNH2 (0.43) | POLBNPSR1EGFRKCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242709-A2 | Antagonists of specific excitatory amino acid neurotransmitter receptors | NOVA PHARMACEUTICAL CORPORATION (US) | 1987-10-28 | — | — | EP | disclosed |
| WO-1987006131-A1 | ANTAGONISTS OF SPECIFIC EXCITATORY AMINO ACID NEUROTRANSMITTER RECEPTORS | RZESZOTARSKI JANUSZ WACLAW (US) | 1987-10-22 | — | — | WO | disclosed |
| US-4657899-A | ANALGESICS, COGNITION ACTIVATORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1987-04-14 | — | — | US | disclosed |