Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 3/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5971737 | 0.88 | ITGB3 (0.66) | ITGB3ITGA2BABCB1ACEDPP4 | |
| SCHEMBL9225882 | 0.86 | DPP4 (0.53) | ITGB3ITGA2BABCB1ACEDPP4 | |
| SCHEMBL10619564 | 0.85 | ITGB3 (0.63) | ITGB3ITGA2BABCB1ACEDPP4 | |
| SCHEMBL7331201 | 0.85 | ACE (0.68) | ITGB3ITGA2BACELMNADPP4 | |
| SCHEMBL7331191 | 0.85 | ACE (0.68) | ITGB3ITGA2BACELMNADPP4 | |
| SCHEMBL7317534 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BABCB1DPP4DPP8 | |
| SCHEMBL11028854 | 0.85 | ACE (0.73) | ITGB3ITGA2BACELMNADPP4 | |
| SCHEMBL7325248 | 0.85 | ACE (0.73) | ITGB3ITGA2BACELMNADPP4 | |
| SCHEMBL7325241 | 0.85 | ACE (0.73) | ITGB3ITGA2BACELMNADPP4 | |
| SCHEMBL11028861 | 0.85 | ACE (0.73) | ITGB3ITGA2BACELMNADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237239-A2 | New compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-09-16 | — | — | EP | disclosed |