Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787712 | 0.93 | HTT (0.45) | HTTMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL1041146 | 0.82 | HTT (0.51) | HTTMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL1044092 | 0.80 | KEAP1 (0.48) | HTTMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3784529 | 0.80 | KEAP1 (0.48) | HTTMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3787513 | 0.77 | HTT (0.50) | HTTMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3778653 | 0.75 | KEAP1 (0.47) | HTTMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3788955 | 0.75 | KEAP1 (0.47) | HTTMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3790848 | 0.75 | KEAP1 (0.47) | HTTMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3785614 | 0.73 | CYP17A1 (0.46) | KMT2ALMNA | |
| SCHEMBL17858939 | 0.72 | MEN1 (0.47) | HTTMEN1KMT2AKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272826-A1 | 2-mercaptopentancarboxylic acid derivatives, the method for preparing them and the pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-01-12 | — | — | EP | disclosed |