Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.34 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10605434 | 1.00 | NFKB1 (0.46) | NFKB1NFKB2RELAPPARGMAPT | |
| SCHEMBL10603470 | 0.86 | NFKB1 (0.49) | NFKB1NFKB2RELAPPARGMAPT | |
| SCHEMBL10608167 | 0.86 | NFKB1 (0.49) | NFKB1NFKB2RELAPPARGMAPT | |
| SCHEMBL10772968 | 0.86 | NFKB1 (0.49) | NFKB1NFKB2RELAPPARGMAPT | |
| SCHEMBL10772965 | 0.86 | NFKB1 (0.49) | NFKB1NFKB2RELAPPARGMAPT | |
| SCHEMBL10603475 | 0.86 | NFKB1 (0.49) | NFKB1NFKB2RELAPPARGMAPT | |
| SCHEMBL10608164 | 0.86 | NFKB1 (0.49) | NFKB1NFKB2RELAPPARGMAPT | |
| SCHEMBL10622161 | 0.82 | PPARG (0.55) | NFKB1NFKB2RELAPPARGMAPT | |
| SCHEMBL10622158 | 0.82 | PPARG (0.55) | NFKB1NFKB2RELAPPARGMAPT | |
| SCHEMBL11009683 | 0.81 | NFKB1 (0.51) | NFKB1NFKB2RELAPPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4689426-A | ANTITUMOR AGENTS, VIRCIDES, BACTERICIDES | TEIJIN LIMITED (JP) | 1987-08-25 | — | — | US | disclosed |
| EP-0131441-A2 | 5-Alkylidene-2-halo-4-substituted-2-cyclopentenone and process for production thereof | TEIJIN LIMITED (JP) | 1985-01-16 | — | — | EP | disclosed |