SCHEMBL10773199

SCHEMBL10773199

CCC(O)CCCCC(O)CCCCO

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
FFAR1 O14842 1/20 0.39
PSMD14 O00487 2/20 0.38
PLA2G1B P04054 2/20 0.38
MMP2 P08253 2/20 0.38
ATG4B Q9Y4P1 2/20 0.38
HSP90AA1 P07900 1/20 0.38
RAD52 P43351 1/20 0.38
NFKB1 P19838 1/20 0.38
GPR84 Q9NQS5 5/20 0.36
PTPN1 P18031 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12531578 0.97 SMN1; SMN2 (0.39) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL429392 0.97
SCHEMBL21552329 0.95 LMNA (0.42) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL483813 0.95 LMNA (0.46) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL6888416 0.95 LMNA (0.46) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL10007983 0.95 LMNA (0.46) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL12491170 0.95 LMNA (0.46) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL20680773 0.95 LMNA (0.46) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL887706 0.95 LMNA (0.46) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL554611 0.95 LMNA (0.46) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9512263-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-12-06 US disclosed
EP-2788394-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-04-06 EP disclosed
US-20140357795-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-12-04 US disclosed
EP-2788394-A2 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-10-15 EP disclosed
WO-2013086480-A2 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-06-13 WO disclosed
US-4637893-A OXYALKYLATION OF INITIATOR COMPOUNDS, PREPARING POLYURETHANES BASF CORPORATION (US) 1987-01-20 US disclosed
EP-0116309-A1 Flexible polyurethane foams having high indentation load deflection prepared from polyol blends BASF WYANDOTTE CORPORATION (US) 1984-08-22 EP disclosed
EP-0114072-A2 Delayed co-initiation process for preparing polyol blends BASF Corporation (US) 1984-07-25 EP disclosed
US-4327194-A Flexible polyurethane foam prepared from a reaction mixture which _includes a polyether triol containing an effectively dispersed finely _divided solid particulate material OLIN CORPORATION (US) 1982-04-27 US disclosed
US-4113706-A Aromatic imino acids and resins derived therefrom THE P. D. GEORGE COMPANY (US) 1978-09-12 US disclosed
US-4081427-A POLYESTER-POLYIMIDE THE P. D. GEORGE COMPANY (US) 1978-03-28 US disclosed
US-4069209-A DIELECTRIC COATINGS FOR WIRES THE P. D. GEORGE COMPANY (US) 1978-01-17 US disclosed