Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555852 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL6888416 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL897366 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL887706 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL554611 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL483813 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL12491170 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| 1,6-Hexanediol SCHEMBL4564056 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL20680773 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL427921 | 1.00 | LMNA (0.46) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981952-B2 | Methods of producing omega-hydroxylated fatty acid derivatives | GENOMATICA, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| US-20240117324-A1 | ACYL-ACP Reductase With Improved Properties | AGAIN BIO APS (DK) | 2024-04-11 | — | — | US | disclosed |
| US-20230167419-A1 | Omega-Hydroxylase-Related Fusion Polypeptides With Improved Properties | AGAIN BIO APS (DK) | 2023-06-01 | — | — | US | disclosed |
| US-20220267813-A1 | Microbial Production Of Fatty Diols | GENOMATICA, INC. | 2022-08-25 | — | — | US | disclosed |
| US-11421206-B2 | Omega-hydroxylase-related fusion polypeptides with improved properties | GENOMATICA, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-11359216-B2 | Microbial production of fatty diols | GENOMATICA, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| US-11339384-B2 | Thioesterase variants having improved activity for the production of medium-chain fatty acid derivatives | GENOMATICA, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| US-20220090028-A1 | ACYL-ACP Reductase With Improved Properties | GENOMATICA, INC. | 2022-03-24 | — | — | US | disclosed |
| US-20210310033-A1 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | AGAIN BIO APS (DK) | 2021-10-07 | — | — | US | disclosed |
| US-11130944-B2 | Acyl-ACP reductase with improved properties | GENOMATICA, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20170029854-A1 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | REG Life Sciences, LLC (US) | 2017-02-02 | — | — | US | disclosed |
| US-20160348080-A1 | ACYL-ACP REDUCTASE WITH IMPROVED PROPERTIES | GENOMATICA, INC. | 2016-12-01 | — | — | US | disclosed |
| EP-3077526-A1 | MICROBIAL PRODUCTION OF FATTY AMINES | REG Life Sciences, LLC (US) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015157719-A9 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | REG Life Sciences, LLC (US) | 2016-08-04 | — | — | WO | disclosed |
| US-20160002681-A1 | ACP-MEDIATED PRODUCTION OF FATTY ACID DERIVATIVES | REG Life Sciences, LLC (US) | 2016-01-07 | — | — | US | disclosed |
| US-20150361454-A1 | ACYL-ACP REDUCTASE WITH IMPROVED PROPERTIES | REG Life Sciences, LLC (US) | 2015-12-17 | — | — | US | disclosed |
| WO-2015157719-A1 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | REG Life Sciences, LLC (US) | 2015-10-15 | — | — | WO | disclosed |
| WO-2015085271-A1 | MICROBIAL PRODUCTION OF FATTY AMINES | REG Life Sciences, LLC (US) | 2015-06-11 | — | — | WO | disclosed |
| US-20150064782-A1 | PRODUCTION OF FATTY ACID DERIVATIVES | REG Life Sciences, LLC (US) | 2015-03-05 | — | — | US | disclosed |
| US-20120172281-A1 | DETERGENT COMPOSITIONS COMPRISING MICROBIALLY PRODUCED FATTY ALCOHOLS AND DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172281-A1 | DETERGENT COMPOSITIONS COMPRISING MICROBIALLY PRODUCED FATTY ALCOHOLS AND DERIVATIVES THEREOF | MGLL, DAGLA, ADH1C | LMNA 2835/4885ALDH1A1 282/4885HSD17B10 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.