Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 15/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063122 | 0.81 | KIF11 (0.58) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL3958081 | 0.81 | KIF11 (0.55) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL3960910 | 0.80 | KIF11 (0.57) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL6110495 | 0.75 | KIF11 (0.54) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL1042272 | 0.74 | KIF11 (0.61) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL6110928 | 0.74 | KIF11 (0.53) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL6111634 | 0.74 | KIF11 (0.49) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4366741 | 0.73 | KIF11 (0.54) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL3496287 | 0.73 | KIF11 (0.48) | KIF11AGTR1AGTR2MAP1LC3BKCNH2 | |
| SCHEMBL4364319 | 0.73 | KIF11 (0.58) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275412-A1 | Indole and benzimidazole derivatives | Novartis Vaccines and Diagnostics, Inc. (US) | 2011-01-19 | — | — | EP | disclosed |