Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FPR1 | P21462 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110495 | 0.79 | KIF11 (0.54) | KIF11KCNH2MAP1LC3B | |
| SCHEMBL3493383 | 0.79 | KIF11 (0.59) | KIF11POLBSMN1; SMN2USP2TSHR | |
| SCHEMBL3493386 | 0.79 | KIF11 (0.59) | KIF11POLBSMN1; SMN2USP2TSHR | |
| SCHEMBL3496879 | 0.78 | KIF11 (0.70) | KIF11POLBSMN1; SMN2AGTR1AGTR2 | |
| SCHEMBL6111634 | 0.76 | KIF11 (0.49) | KIF11KCNH2MAP1LC3B | |
| SCHEMBL6110928 | 0.76 | KIF11 (0.53) | KIF11KCNH2MAP1LC3B | |
| SCHEMBL4366741 | 0.74 | KIF11 (0.54) | KIF11KCNH2MAP1LC3B | |
| SCHEMBL1077328 | 0.73 | KIF11 (0.48) | KIF11AGTR1AGTR2CNR1CNR2 | |
| SCHEMBL5756374 | 0.73 | KIF11 (0.44) | KIF11PPARGKCNH2MAP1LC3B | |
| SCHEMBL5751482 | 0.73 | KIF11 (0.57) | KIF11KCNH2MAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093767-A1 | Mitotic Kinase Inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093767-A1 | Mitotic Kinase Inhibitors | BUB1B, BUB1, PLK1 | KIF11 18/4885POLB 490/4885SMN1; SMN2 1668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.