Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.43 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.42 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | RAMP3 | O60896 | 5/20 | 0.42 |
| ▸ | CALCR | P30988 | 5/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10773608 | 1.00 | APLNR (0.43) | APLNRKEAP1NMUR2NMUR1CXCR4 | |
| SCHEMBL30683558 | 0.87 | CALCRL (0.46) | KEAP1CXCR4RAMP3CALCRCALCRL | |
| SCHEMBL30435240 | 0.85 | NTSR2 (0.46) | — | |
| SCHEMBL30240004 | 0.84 | DPP4 (0.47) | — | |
| SCHEMBL30449622 | 0.84 | KEAP1 (0.48) | KEAP1RAMP3CALCRCALCRL | |
| SCHEMBL30136886 | 0.84 | NTSR2 (0.46) | CALCRL | |
| SCHEMBL30444071 | 0.84 | BACE1 (0.45) | CALCRL | |
| SCHEMBL30532203 | 0.83 | CALCRL (0.45) | KEAP1CALCRL | |
| SCHEMBL30435100 | 0.83 | CAPN1 (0.45) | NMUR2 | |
| SCHEMBL30443912 | 0.83 | CALCRL (0.48) | KEAP1NMUR2NMUR1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1987006239-A1 | HEPATOMA-DERIVED GROWTH FACTOR | THE GENERAL HOSPITAL CORPORATION (US) | 1987-10-22 | — | — | WO | claimed |