Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715276 | 0.77 | SLC6A4 (0.53) | SLC6A4HRH3HTR2CSLC6A2HTR2B | |
| SCHEMBL1077402 | 0.76 | SLC6A4 (0.49) | SLC6A4HRH3EED | |
| SCHEMBL1036117 | 0.75 | SLC6A4 (0.54) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL4462917 | 0.71 | SLC6A2 (0.35) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29356733 | 0.70 | MEN1 (0.60) | SLC6A4HRH3HTR2CSLC6A2SLC6A3 | |
| SCHEMBL11639387 | 0.70 | MEN1 (0.60) | SLC6A4HRH3HTR2CSLC6A2SLC6A3 | |
| SCHEMBL1037048 | 0.70 | SLC6A4 (0.54) | SLC6A4HRH3 | |
| Hydrochloric Acid SCHEMBL11798762 | 0.70 | SLC6A4 (0.53) | SLC6A4HRH3HTR2CSLC6A2SLC6A3 | |
| SCHEMBL11715785 | 0.69 | NR4A1 (0.36) | SLC6A4HTR2CEEDSLC6A2HTR2B | |
| SCHEMBL1037518 | 0.69 | SLC6A4 (0.53) | SLC6A4HRH3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831173-B1 | TETRAHYDROISOQUINOLINE COMPOUNDS FOR TREATMENT OF CNS DISORDERS | JANSSEN PHARMACEUTICA NV (BE) | 2011-01-26 | — | — | EP | disclosed |