SCHEMBL1077408

SCHEMBL1077408

C=CCOP(=O)(Cc1ccccc1)OC=C

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.36
PKM P14618 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.36
CYP3A4 P08684 2/20 0.34
KLK8 O60259 1/20 0.33
PLAU P00749 1/20 0.33
KLK2 P20151 1/20 0.33
KLK4 Q9Y5K2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CETP P11597 3/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LIG1 P18858 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9650634 0.90 HPGD (0.41) HPGDALOX15PKMSMN1; SMN2TSHR
SCHEMBL7895286 0.86 HPGD (0.44) HPGDALOX15TSHRCYP3A4KLK8
SCHEMBL11312153 0.84 MEN1 (0.38) HPGDALOX15PKMSMN1; SMN2TSHR
SCHEMBL11327658 0.83 NPY5R (0.45) HPGD
SCHEMBL11316177 0.81 CETP (0.40) CETP
SCHEMBL11318193 0.80 POLB (0.42) HPGDALOX15PKMSMN1; SMN2TSHR
SCHEMBL11313180 0.80 MEN1 (0.45) HPGDALOX15PKMSMN1; SMN2TSHR
SCHEMBL11319844 0.79 NPSR1 (0.39) HPGDALOX15PKMSMN1; SMN2TSHR
SCHEMBL9449517 0.77 TSHR (0.46) HPGDALOX15PKMSMN1; SMN2TSHR
SCHEMBL2052517 0.73 FDPS (0.36) TSHRCYP3A4KLK8PLAUKLK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE42389-E1 Substrate design for optimized performance of up-conversion phosphors utilizing proper thermal management UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-05-24 US claimed
US-RE42076-E1 copolymerizing alkyl acrylate or alkyl methacrylate with dialkyl vinylbenzyl phosphonic acid diester or vinylbenzyl phosphonic acid to form a copolymer, dispersing luminescent metal ions ( NAYF4:ErYb) in the co-polymer without cracking and delaminating of the co-polymer; optical fiber amplifier UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-01-25 US claimed
US-6844387-B2 Copolymer composite of alkyl material and phosphonate with luminescent metal ions dispersed in composite; can be used for displays without cracking and delaminating of the copolymer UNIVERSITY OF CENTRAL FLORIDA (US) 2005-01-18 US claimed
US-20020020830-A1 Composites of inorganic luminophores stabilized in polymer hosts RESEARCH FOUNDATION OF THE UNIVERSITY OF 2002-02-21 US claimed
US-RE42389-E1 Substrate design for optimized performance of up-conversion phosphors utilizing proper thermal management UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-05-24 US disclosed
US-RE42076-E1 copolymerizing alkyl acrylate or alkyl methacrylate with dialkyl vinylbenzyl phosphonic acid diester or vinylbenzyl phosphonic acid to form a copolymer, dispersing luminescent metal ions ( NAYF4:ErYb) in the co-polymer without cracking and delaminating of the co-polymer; optical fiber amplifier UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-01-25 US disclosed
US-7075707-B1 Substrate design for optimized performance of up-conversion phosphors utilizing proper thermal management RESEARCH FOUNDATION OF THE UNIVERSITY OF CENTRAL FLORIDA, INCORPORATED (US) 2006-07-11 US disclosed
US-6844387-B2 Copolymer composite of alkyl material and phosphonate with luminescent metal ions dispersed in composite; can be used for displays without cracking and delaminating of the copolymer UNIVERSITY OF CENTRAL FLORIDA (US) 2005-01-18 US disclosed
US-20020020830-A1 Composites of inorganic luminophores stabilized in polymer hosts RESEARCH FOUNDATION OF THE UNIVERSITY OF 2002-02-21 US disclosed