Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KLK8 | O60259 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KLK2 | P20151 | 1/20 | 0.37 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077408 | 0.86 | HPGD (0.37) | HPGDTSHRKLK8PLAUKLK2 | |
| SCHEMBL966722 | 0.81 | HPGD (0.46) | HPGDTSHRALOX15 | |
| SCHEMBL2527139 | 0.79 | HPGD (0.44) | HPGDTSHRALOX15 | |
| SCHEMBL11437838 | 0.79 | HPGD (0.44) | HPGDTSHRCYP3A4CYP2C19MEN1 | |
| SCHEMBL9650634 | 0.77 | HPGD (0.41) | HPGDTSHRKLK8PLAUKLK2 | |
| SCHEMBL20377363 | 0.74 | HPGD (0.50) | HPGDTSHRCYP3A4CYP2C19MEN1 | |
| SCHEMBL29050754 | 0.72 | HPGD (0.48) | HPGDTSHRKLK8PLAUKLK2 | |
| SCHEMBL21638768 | 0.72 | HPGD (0.48) | HPGDTSHRKLK8PLAUKLK2 | |
| SCHEMBL21638771 | 0.72 | HPGD (0.48) | HPGDTSHRKLK8PLAUKLK2 | |
| SCHEMBL563700 | 0.72 | HPGD (0.48) | HPGDTSHRKLK8PLAUKLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187838-B1 | KIT FOR TEETH MAINTENANCE | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION | 2001-02-13 | — | — | US | disclosed |
| US-6001897-A | ENAMEL COATING FOR TEETH | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1999-12-14 | — | — | US | disclosed |