Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23489726 | 0.82 | CTSL (0.62) | CTSSCTSLPOLBGFERCTSB | |
| SCHEMBL7275964 | 0.82 | POLB (0.74) | CTSSCTSLPOLBGFERCTSB | |
| SCHEMBL5193787 | 0.82 | POLB (0.74) | CTSSCTSLPOLBGFERCTSB | |
| SCHEMBL7268468 | 0.80 | POLB (0.76) | CTSSCTSLPOLBGFERCTSB | |
| SCHEMBL7268474 | 0.80 | POLB (0.76) | CTSSCTSLPOLBGFERCTSB | |
| SCHEMBL25004070 | 0.80 | CTSS (0.61) | CTSSCTSLPOLBGFERCTSB | |
| SCHEMBL7408631 | 0.80 | CTSS (0.61) | CTSSCTSLPOLBGFERCTSB | |
| SCHEMBL7404835 | 0.80 | CTSS (0.61) | CTSSCTSLPOLBGFERCTSB | |
| SCHEMBL7607635 | 0.79 | POLB (0.66) | CTSSCTSLPOLBGFERCTSB | |
| SCHEMBL10778417 | 0.78 | CTSS (0.62) | CTSSCTSLPOLBGFERCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249096-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1987-12-16 | — | — | EP | disclosed |