SCHEMBL10774292

SCHEMBL10774292

Cc1ccc(-c2ccc(C(C)(c3ccc(O)cc3)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.59
ESR2 Q92731 6/20 0.59
ACHE P22303 1/20 0.56
TSHR P16473 2/20 0.50
CYP3A4 P08684 2/20 0.50
KIF11 P52732 1/20 0.50
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
AR P10275 1/20 0.50
HPGD P15428 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR6 P50406 1/20 0.50
ESRRG P62508 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.43
MAOA P21397 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3143096 0.93 ESR2 (0.67) ESR1ESR2ACHETSHRCYP3A4
SCHEMBL13815221 0.93 ESR2 (0.67) ESR1ESR2ACHETSHRCYP3A4
SCHEMBL10772499 0.91 ESR1 (0.70) ESR1ESR2TSHRCYP3A4KIF11
SCHEMBL26136547 0.91 ESR1 (0.70) ESR1ESR2TSHRCYP3A4KIF11
SCHEMBL12004872 0.91 ESR1 (0.70) ESR1ESR2TSHRCYP3A4KIF11
SCHEMBL2385710 0.87 ESR1 (0.70) ESR1ESR2ACHETSHRCYP3A4
SCHEMBL12299307 0.87 ESR1 (0.70) ESR1ESR2ACHETSHRCYP3A4
SCHEMBL22782579 0.87 ESR1 (0.70) ESR1ESR2ACHETSHRCYP3A4
SCHEMBL19901313 0.87 ESR1 (0.70) ESR1ESR2ACHETSHRCYP3A4
SCHEMBL822977 0.85 ESR1 (0.83) ESR1ESR2ACHETSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4707464-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-11-17 US disclosed