SCHEMBL12299307

SCHEMBL12299307

Cc1ccc(C(C)(c2ccc(O)cc2)c2ccc(C(C)(C)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.70
ESR2 Q92731 10/20 0.70
CYP3A4 P08684 2/20 0.70
TSHR P16473 2/20 0.70
HPGD P15428 2/20 0.70
HSD17B10 Q99714 2/20 0.70
AR P10275 1/20 0.70
SLC6A2 P23975 1/20 0.70
SLC6A4 P31645 1/20 0.70
HTR6 P50406 1/20 0.70
ESRRG P62508 1/20 0.70
SLC6A3 Q01959 1/20 0.70
ALDH1A1 P00352 2/20 0.59
ACHE P22303 1/20 0.56
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
SHBG P04278 1/20 0.42
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22782579 1.00 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL19901313 1.00 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL2385710 1.00 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL13815221 0.93 ESR2 (0.67) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL3143096 0.93 ESR2 (0.67) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL1101874 0.93 ESR1 (0.80) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL822914 0.93 ESR1 (0.80) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL35973 0.91 ESR1 (0.84) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL10774292 0.87 ESR1 (0.59) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL14922956 0.87 ESR1 (0.70) ESR1ESR2CYP3A4TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9857682-B2 Positive photosensitive siloxane resin composition and display device formed using the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-02 US disclosed
US-20160195810-A1 POSITIVE PHOTOSENSITIVE SILOXANE RESIN COMPOSITION AND DISPLAY DEVICE FORMED USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-07 US disclosed
US-8026042-B2 Polymer for organic anti-reflective coating layer and composition including the same DONGJIN SEMICHEM CO., LTD. (KR) 2011-09-27 US disclosed
US-20110003478-A1 POLYMER FOR ORGANIC ANTI-REFLECTIVE COATING LAYER AND COMPOSITION INCLUDING THE SAME KIM SANG-JEOUNG 2011-01-06 US disclosed