Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 11/20 | 0.67 |
| ▸ | ESR1 | P03372 | 10/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | ESRRG | P62508 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143096 | 1.00 | ESR2 (0.67) | ESR2ESR1ACHETSHRCYP3A4 | |
| SCHEMBL12299307 | 0.93 | ESR1 (0.70) | ESR2ESR1ACHETSHRCYP3A4 | |
| SCHEMBL22782579 | 0.93 | ESR1 (0.70) | ESR2ESR1ACHETSHRCYP3A4 | |
| SCHEMBL19901313 | 0.93 | ESR1 (0.70) | ESR2ESR1ACHETSHRCYP3A4 | |
| SCHEMBL10774292 | 0.93 | ESR1 (0.59) | ESR2ESR1ACHETSHRCYP3A4 | |
| SCHEMBL2385710 | 0.93 | ESR1 (0.70) | ESR2ESR1ACHETSHRCYP3A4 | |
| SCHEMBL822977 | 0.91 | ESR1 (0.83) | ESR2ESR1ACHETSHRCYP3A4 | |
| SCHEMBL22335854 | 0.89 | ESR1 (0.80) | ESR2ESR1ACHETSHRCYP3A4 | |
| SCHEMBL21694220 | 0.89 | ESR1 (0.55) | ESR2ESR1ACHETSHRCYP3A4 | |
| SCHEMBL18750 | 0.89 | ESR1 (0.80) | ESR2ESR1ACHETSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090153021-A1 | LARGE-BANDGAP HOST MATERIALS FOR PHOSPHORESCENT EMITTERS | WASHINGTON, UNIVERSITY OF (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090153021-A1 | LARGE-BANDGAP HOST MATERIALS FOR PHOSPHORESCENT EMITTERS | IQGAP1, SGTA, DPAGT1 | ESR2 826/4885ESR1 967/4885ACHE 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.