Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.61 |
| ▸ | PPARD | Q03181 | 5/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27782107 | 0.85 | ZDHHC7 (0.49) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL10780877 | 0.84 | GPR84 (0.44) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL4601843 | 0.82 | GPR84 (0.68) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL3949092 | 0.82 | GPR84 (0.68) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL3955262 | 0.82 | GPR84 (0.68) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL9159327 | 0.81 | FFAR4 (0.69) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL8914351 | 0.81 | ZDHHC7 (0.57) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL4957082 | 0.79 | GPR84 (0.63) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL1483983 | 0.79 | GPR84 (0.63) | GPR84PPARDLCKZDHHC20ZDHHC2 | |
| SCHEMBL23829862 | 0.79 | GPR84 (0.62) | GPR84PPARDLCKZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710468-A | FROM OPTICALLY ACTIVE SUBSTITUTED HYDROXYBUTYRIC ACID DERIVATIVES WITH OXIDOREDUCTASE | SIGMA-TAU INDUSTRIE PHARMACEUTICHE RIUNITE S.P.A. (IT) | 1987-12-01 | — | — | US | disclosed |