SCHEMBL3949092

SCHEMBL3949092

CCCCCCCCCCCC(O)C(O)CC(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 9/20 0.68
FFAR1 O14842 2/20 0.55
FFAR4 Q5NUL3 1/20 0.55
SPHK1 Q9NYA1 2/20 0.50
PPARD Q03181 3/20 0.48
MAPT P10636 2/20 0.48
LCK P06239 1/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.48
ZDHHC2 Q9UIJ5 1/20 0.48
CYP2D6 P10635 2/20 0.47
GMNN O75496 1/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
THPO P40225 1/20 0.47
MTOR P42345 1/20 0.47
BLM P54132 1/20 0.47
KDM4E B2RXH2 1/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4601843 1.00 GPR84 (0.68) GPR84FFAR1FFAR4SPHK1PPARD
SCHEMBL3955262 1.00 GPR84 (0.68) GPR84FFAR1FFAR4SPHK1PPARD
SCHEMBL14885535 0.91 GPR84 (0.55) GPR84FFAR1FFAR4ALDH1A1TSHR
SCHEMBL28284749 0.84 GPR84 (0.63) GPR84FFAR1FFAR4SPHK1PPARD
SCHEMBL19611417 0.84 GPR84 (0.63) GPR84FFAR1FFAR4SPHK1PPARD
SCHEMBL1483983 0.84 GPR84 (0.63) GPR84FFAR1FFAR4SPHK1PPARD
SCHEMBL4957082 0.84 GPR84 (0.63) GPR84FFAR1FFAR4SPHK1PPARD
SCHEMBL8633366 0.83 FFAR4 (0.78) GPR84FFAR1FFAR4PPARDMAPT
SCHEMBL1274520 0.83 FFAR4 (0.78) GPR84FFAR1FFAR4PPARDMAPT
SCHEMBL4402579 0.83 FFAR4 (0.78) GPR84FFAR1FFAR4PPARDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7556960-B2 Pseudomycin production by pseudomonas syringae ELI LILLY AND COMPANY (US) 2009-07-07 US disclosed
EP-1173471-B1 PSEUDOMYCIN ANALOGS LILLY CO ELI (US) 2008-04-30 EP disclosed
US-20080090731-A1 PSEUDOMYCINS USEFUL AGAINST PLANT DISEASES MONTANA STATE UNIVERSITY 2008-04-17 US disclosed
US-7326689-B2 Pseudomycins useful against plant diseases ELI LILLY AND COMPANY (US) 2008-02-05 US disclosed
WO-2007095259-A2 ANTIMYCOTIC RHAMNOLIPID COMPOSITIONS AND RELATED METHODS OF USE JENEIL BIOTECH, INC. (US) 2007-08-23 WO disclosed
US-20070191292-A1 Antimycotic rhamnolipid compositions and related methods of use JENEIL BIOTECH, INC. 2007-08-16 US disclosed
EP-1171576-B1 PSEUDOMYCIN PRODUCTION BY PSEUDOMONAS SYRINGAE LILLY CO ELI (US) 2007-07-11 EP disclosed
US-20060257973-A1 Pseudomycin production by pseudomonas syringae ELI LILLY AND COMPANY 2006-11-16 US disclosed
US-6919188-B1 Pseudomycin production by Pseudomonas syringae ELI LILLY AND COMPANY (US) 2005-07-19 US disclosed
EP-1326494-B1 PSEUDOMYCINS USEFUL AGAINST PLANT DISEASES UNIV MONTANA RES DEV INST (US) 2005-05-18 EP disclosed
US-20030008814-A1 Pseudomycin phosphate prodrugs ELI LILLY AND COMPANY 2003-01-09 US disclosed
CN-1360505-A Pseudomycin antifungal compositions and methods of their use LILLY CO ELI (US) 2002-07-24 CN disclosed
CN-1355812-A Pseudomycin analogs LILLY CO ELI (US) 2002-06-26 CN disclosed
WO-2002015696-A2 PSEUDOMYCINS USEFUL AGAINST PLANT DISEASES RESEARCH AND DEVELOPMENT INSTITUTE, INC. (US) 2002-02-28 WO disclosed
EP-1173471-A2 PSEUDOMYCIN ANALOGS ELI LILLY AND COMPANY (US) 2002-01-23 EP disclosed
EP-1171150-A2 PSEUDOMYCIN ANTIFUNGAL COMPOSITIONS AND METHODS FOR THEIR USE ELI LILLY AND COMPANY (US) 2002-01-16 EP disclosed
EP-1171576-A1 PSEUDOMYCIN PRODUCTION BY $i(PSEUDOMONAS SYRINGAE) ELI LILLY AND COMPANY (US) 2002-01-16 EP disclosed
WO-2000062793-A2 PSEUDOMYCIN ANTIFUNGAL COMPOSITIONS AND METHODS FOR THEIR USE ELI LILLY AND COMPANY (US) 2000-10-26 WO disclosed
WO-2000063345-A1 PSEUDOMYCIN PRODUCTION BY $i(PSEUDOMONAS SYRINGAE) ELI LILLY AND COMPANY (US) 2000-10-26 WO disclosed
WO-2000063237-A2 PSEUDOMYCIN ANALOGS ELI LILLY AND COMPANY (US) 2000-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008814-A1 Pseudomycin phosphate prodrugs PMM2, ME1, BPGM GPR84 2705/4885FFAR1 2857/4885FFAR4 3071/4885
US-20060257973-A1 Pseudomycin production by pseudomonas syringae MRPL21, MGAM, MRPS18A GPR84 3854/4885FFAR1 3715/4885FFAR4 4156/4885
US-20080090731-A1 PSEUDOMYCINS USEFUL AGAINST PLANT DISEASES MGAM, PMM2, MANBA GPR84 4485/4885FFAR1 4721/4885FFAR4 4723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.