Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | EPHB3 | P54753 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078373 | 0.83 | NPC1 (0.50) | NPC1PKMRAB9AKMT2ALMNA | |
| SCHEMBL1079481 | 0.75 | ALDH1A1 (0.55) | NPC1RAB9AKMT2ALMNAMAPT | |
| SCHEMBL9214998 | 0.72 | KDM4E (0.53) | NPC1RAB9AKMT2AEPHB3LMNA | |
| SCHEMBL5201549 | 0.72 | GRM5 (0.62) | NPC1RAB9AKMT2ALMNAMAPT | |
| SCHEMBL8569632 | 0.71 | TRPV1 (0.58) | RAB9AKMT2AEPHB3LMNAMAPT | |
| SCHEMBL9588701 | 0.70 | MAPT (0.51) | NPC1RAB9AKMT2AEPHB3LMNA | |
| SCHEMBL27348211 | 0.70 | KDM4E (0.56) | NPC1PKMRAB9AKMT2AEPHB3 | |
| SCHEMBL16404225 | 0.70 | CNR2 (0.56) | NPC1RAB9AKMT2AEPHB3LMNA | |
| SCHEMBL9215003 | 0.69 | MAPT (0.50) | NPC1RAB9AKMT2AEPHB3LMNA | |
| SCHEMBL13881198 | 0.69 | RAB9A (1.00) | NPC1RAB9AKMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005052-A2 | NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN GROSS CORPORATION (KR) | 2011-01-13 | — | — | WO | disclosed |