Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236851 | 1.00 | CA2 (0.45) | CA2MAPK1GPR84FFAR1SLC1A3 | |
| SCHEMBL10780887 | 0.92 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10775582 | 0.92 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL6239027 | 0.88 | TDP1 (0.44) | CA2MAPK1GPR84FFAR1SLC1A3 | |
| SCHEMBL10778879 | 0.88 | TDP1 (0.44) | CA2MAPK1GPR84FFAR1SLC1A3 | |
| SCHEMBL22552932 | 0.85 | CA2 (0.50) | CA2MAPK1GPR84FFAR1SLC1A3 | |
| SCHEMBL22552930 | 0.85 | CA2 (0.50) | CA2MAPK1GPR84FFAR1SLC1A3 | |
| SCHEMBL48780 | 0.83 | CA2 (0.48) | CA2MAPK1GPR84FFAR1SLC1A3 | |
| SCHEMBL28099107 | 0.83 | CA2 (0.54) | CA2MAPK1GPR84FFAR1SLC1A3 | |
| SCHEMBL24257290 | 0.82 | GPR84 (0.55) | CA2MAPK1GPR84FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710468-A | FROM OPTICALLY ACTIVE SUBSTITUTED HYDROXYBUTYRIC ACID DERIVATIVES WITH OXIDOREDUCTASE | SIGMA-TAU INDUSTRIE PHARMACEUTICHE RIUNITE S.P.A. (IT) | 1987-12-01 | — | — | US | disclosed |