Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10364878 | 0.91 | ADRB2 (0.73) | ADRB2ADRB1ADRB3CYP1A2ATM | |
| SCHEMBL10772317 | 0.89 | ADRB2 (0.65) | ADRB2ADRB1ADRB3CYP1A2ATM | |
| Hydrochloric Acid SCHEMBL10772403 | 0.88 | ADRB2 (0.64) | ADRB2ADRB1ADRB3CYP1A2ATM | |
| SCHEMBL10773150 | 0.85 | ADRB1 (0.81) | ADRB2ADRB1ADRB3CYP1A2ATM | |
| Hydrochloric Acid SCHEMBL10776063 | 0.84 | ADRB1 (0.80) | ADRB2ADRB1ADRB3CYP1A2ATM | |
| SCHEMBL10772438 | 0.83 | ADRB1 (0.67) | ADRB2ADRB1ADRB3CYP1A2ATM | |
| Hydrochloric Acid SCHEMBL10772347 | 0.82 | ADRB1 (0.65) | ADRB2ADRB1ADRB3CYP1A2ATM | |
| SCHEMBL5565079 | 0.80 | ADRB2 (0.80) | ADRB2ADRB1ADRB3CYP1A2ATM | |
| SCHEMBL10778131 | 0.79 | ADRB2 (0.63) | ADRB2ADRB1ADRB3CYP1A2ATM | |
| Hydrochloric Acid SCHEMBL10346456 | 0.79 | ADRB1 (0.78) | ADRB2ADRB1ADRB3CYP1A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210849-A1 | 2-Hydroxy-3-phenoxypropyl amines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-04 | — | — | EP | disclosed |