Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10466223 | 1.00 | MEN1 (0.45) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL10778892 | 0.93 | CTSL (0.44) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL10467639 | 0.93 | CTSL (0.44) | MEN1KMT2ALMNACTSLCTSS | |
| Methoxymethane SCHEMBL10468364 | 0.81 | CYP3A4 (0.43) | MEN1KMT2ALMNACTSLCTSS | |
| Methoxymethane SCHEMBL10772620 | 0.81 | CYP3A4 (0.43) | MEN1KMT2ALMNACTSLCTSS | |
| Methoxymethane SCHEMBL10775780 | 0.80 | KDM4E (0.50) | MEN1KMT2ALMNACTSLCTSS | |
| Methoxymethane SCHEMBL10467400 | 0.80 | KDM4E (0.50) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL10775727 | 0.79 | TSHR (0.38) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL10772587 | 0.79 | KDM4E (0.48) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL10467554 | 0.79 | KDM4E (0.48) | MEN1KMT2ALMNACTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243122-A2 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |