Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 16/20 | 0.70 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | FADS1 | O60427 | 1/20 | 0.57 |
| ▸ | CALML3 | P27482 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30063909 | 0.89 | MAOA (0.71) | GRM2MAOAMAOBFADS1CALML3 | |
| SCHEMBL3087781 | 0.89 | MAOA (0.71) | GRM2MAOAMAOBFADS1CALML3 | |
| SCHEMBL1557298 | 0.89 | MAOA (0.71) | GRM2MAOAMAOBFADS1CALML3 | |
| SCHEMBL1032517 | 0.89 | MAOA (0.71) | GRM2MAOAMAOBFADS1CALML3 | |
| SCHEMBL14214167 | 0.87 | GRM2 (0.82) | GRM2MAOAMAOBFADS1 | |
| SCHEMBL14573697 | 0.87 | GRM2 (0.82) | GRM2MAOAMAOBFADS1 | |
| SCHEMBL6644912 | 0.85 | GRM2 (0.65) | GRM2MAOAMAOBFADS1CALML3 | |
| SCHEMBL27576680 | 0.84 | GRM2 (0.70) | GRM2MAOAMAOBFADS1 | |
| SCHEMBL6233611 | 0.84 | GRM2 (0.66) | GRM2MAOAMAOBFADS1CALML3 | |
| SCHEMBL2896939 | 0.84 | GRM2 (0.66) | GRM2MAOAMAOBFADS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904489-B1 | PROCESS FOR THE SYNTHESIS OF TRIAZOLES | RIB X PHARMACEUTICALS INC (US) | 2011-01-26 | — | — | EP | disclosed |