SCHEMBL6233611

SCHEMBL6233611

NCC1CN(c2cccc(F)c2)C(=O)O1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 9/20 0.66
FADS1 O60427 3/20 0.60
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
F10 P00742 1/20 0.51
BPTF Q12830 1/20 0.50
CALML3 P27482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2896939 1.00 GRM2 (0.66) GRM2FADS1MAOAMAOBF10
SCHEMBL27915892 0.86 GRM2 (0.66) GRM2FADS1MAOAMAOBCALML3
SCHEMBL1557298 0.86 MAOA (0.71) GRM2FADS1MAOAMAOBCALML3
SCHEMBL14769778 0.86 GRM2 (0.73) GRM2FADS1MAOAMAOB
SCHEMBL1032517 0.86 MAOA (0.71) GRM2FADS1MAOAMAOBCALML3
SCHEMBL30063909 0.86 MAOA (0.71) GRM2FADS1MAOAMAOBCALML3
SCHEMBL3087781 0.86 MAOA (0.71) GRM2FADS1MAOAMAOBCALML3
SCHEMBL2896810 0.85 F10 (0.52) GRM2FADS1MAOAMAOBF10
SCHEMBL2901464 0.85 F10 (0.52) GRM2FADS1MAOAMAOBF10
SCHEMBL5618040 0.84 F10 (0.50) GRM2FADS1MAOAMAOBF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603904-A1 ANTIBACTERIAL 1, 3- OXAZOLIDIN -2- ONE DERIVATIVES AstraZeneca AB (SE) 2005-12-14 EP disclosed
WO-2004083205-A1 ANTIBACTERIAL 1, 3- OXAZOLIDIN -2- ONE DERIVATIVES ASTRAZENECA AB (SE) 2004-09-30 WO disclosed
US-6689779-B2 PYRIDINE OR PYRIMIDINE SUBSTITUTED; ANTIBACTERIAL ACTIVITY; LOW TOXICITY DONG A PHARM. CO., LTD. (KR) 2004-02-10 US disclosed
US-20030166620-A1 Novel oxazolidinone derivatives and a process for the preparation thereof DONG A PHARM. CO., LTD. (KR) 2003-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166620-A1 Novel oxazolidinone derivatives and a process for the preparation thereof OXA1L, ODC1, PDCD4 GRM2 4033/4885FADS1 3702/4885MAOA 763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.